Hydrochlorothiazide 25 mg helps treat high blood pressure(hypertension). It also treats Edema related to liver, heart, lung, or kidney disease. This tablet lowers the excessive fluid levels present in the body and treats fluid overload (Edema). This tablet will flush out excess water via urine. It may be used as a single medicine or with other medicines.

Take this medicine as prescribed by a medical expert. It is better to follow the correct dose & duration and not stop taking this tablet in between the treatment course.


Overview -Hydrochlorothiazide 25 mg

  • Hydrochlorothiazide 25mg is an oral tablet that is available in medical stores and online stores as a generic medicine.
  • It comes in the form of a capsule and tablet which you need to take orally.
  • This tablet treats high BP & swelling that occurs due to liver damage, heart failure, and some other medicines.
  • It is a drug available with a prescription only.

You can get this medicine in tablet form as a generic medicine and generic medicines cost less.


  • Treats Edema
  • Treats High BP


How does Hydrochlorothiazide 25 mg tablet work?

The tablet helps lower blood pressure by throwing out excess water and some electrolytes from your body. After a while, it also relaxes your blood vessels and enhances blood flow. This tablet elevates the output of urine to lower blood pressure.

Once your blood pressure is under control, it reduces the risks of heart stroke, heart attack, and kidney problems. Take this tablet as per the prescription of the medical expert.

This tablet also treats Edema, a condition that occurs when your body retains excess water. This tablet helps you eliminate excess water & electrolytes from the body by increasing urine production. It helps the body to throw out extra water and get relief from different symptoms like swelling in the abdomen, legs, and arms and breathlessness.

Hence, it enables you to perform routine tasks easily. Taking Hydrochlorothiazide 25mg tablet along with regular exercise and a healthy lifestyle will give you maximum benefits.


How to use Hydrochlorothiazide 25 mg tablet?

Take this medicine as per the prescription given by the medical expert. Crushing, chewing, or breaking the tablet is not advisable. You need to take it as a whole tablet.



What if you miss a dose of Hydrochlorothiazide 25 mg?

If you miss taking a dose of this tablet, take it once you realize it. If you have the next dose in your schedule and it is nearing, return to the normal dosing schedule and ignore the missed dose. Avoid duplication of doses to cover up the missed dose.

What if you take an extra dose of this tablet(overdose)?

If you take an extra dose of this medicine, call medical help urgently. Some overdose symptoms are dry mouth, muscle pain, nausea, thirst, muscle weakness, or dizziness.



  • Nausea
  • Headache
  • Dizziness
  • Changed blood lipid level
  • Weakness



Hydrochlorothiazide 25mg can boost the chances of skin cancer. So, avoid using tanning beds or going out in the sun.  if you have to go out in the sun, use effective sunscreen with SPF 30 or above and try to wear protective clothing while going outdoors. Your medical expert may ask you to undergo skin tests regularly.

Avoid drinking alcohol with this medicine as it can lead to side effects. Do not rise fast if you are in a lying or a sitting position else you may experience dizziness. Do not get dehydrated or overheated during a workout or while in hot weather. Try to drink sufficient fluids during workouts or while being outdoors in hot weather.

Ask your medical expert to know what type of liquids you can drink and in what quantity. This is because in some people, drinking excess liquid may not be safe same as drinking liquids in fewer amounts.


What are the drug interactions for this tablet?

Taking Hydrochlorothiazide 25 mg in in combination with other medicines causing light-headedness can make the effect severe. Check with your medical expert before taking a sleeping pill, opioid medication, muscle relaxer, or drugs for seizures or anxiety.

So, discuss with your medical expert if you are taking other medicines mainly:

  • Insulin/oral diabetes medication
  • Colestipol, cholestyramine
  • Other medicines for blood pressure
  • Steroid medicine
  • Lithium
  • NSAIDs



Alcohol consumption with this tablet can lower your blood pressure considerably. You may feel dizzy while rising from a lying or sitting position.

Kidney problems

Be extra alert while taking this tablet if your kidney function is affected. This tablet is flushed out from the body through your kidneys. So, if your kidneys aren’t functioning well, this tablet can accumulate in your body leading to more side effects. In case your kidney function is affected badly, the medical expert may halt your treatment using this tablet.

Liver problems

Liver patients should be cautious if they have progressive liver problems or affected liver function. Hydrochlorothiazide 25 mg can result in an imbalance of fluid and electrolytes which can worsen your liver function.


This tablet can erupt lupus problems.

Pregnant women

Speak to your medical professional if you are trying to get pregnant or are already pregnant.

Breastfeeding women

This tablet can travel to breast milk and result in side effects in your child whom you are breastfeeding. So, speak to your medical expert if you are a nursing mother as he may determine whether to halt breastfeeding or discontinue this tablet.

Senior citizens

Any medicine will process slowly in older patients. A normal dose of this tablet for adults can remain for longer in an older body. So, older adults need a lower dose with a different dosing schedule.


General Tips

  • Take Hydrochlorothiazide 25 mg in the morning rather than in the evening so that you don’t have to get up to urinate at night.
  • This tablet causes dizziness, so avoid doing activities that need concentration.
  • The tablet can lead to a fall in sodium levels in the blood. So, avoid taking low-sodium meals while you are taking this tablet.
  • Check your blood pressure after you start with this tablet and inform your medical expert if your BP doesn’t reduce.



Q-For how long Hydrochlorothiazide 25 mg tablet will remain in my system?

It takes nearly 3.5 days for this tablet to be flushed out of the body. This tablet’s half-life for elimination is 6 to 15 hours. This period helps know the exact duration after which the medicine will be thrown out of the body.

Q-Do I need to drink enough water while taking Hydrochlorothiazide 25 mg tablet?

Yes. You should drink enough water in the correct amount daily while taking this tablet. If you are doing exercise or out in the hot sun, make sure you stay hydrated combination of sweating and this tablet can cause fluid loss and a drop in blood pressure to a greater extent.

Q-Is Hydrochlorothiazide 25 mg tablet safe for use in patients with kidney problems?

This tablet is a water pill that treats edema and high blood pressure. This medicine can lead to dehydration and infection and swelling of the kidney.

Q-What will happen if I take this tablet at night?

 If you take this medicine before bedtime, you will have to get up to urinate. So, take it 4 hours before going to bed or in the morning. The dosage for this medicine is based on how you respond to the treatment and your health condition.

Q-Is this tablet safe for heart patients?

This tablet alone or sometimes with other medicines reduces high blood pressure. Well, high blood pressure contributes to the burden of arteries and the heart. So, if the high BP problem stays for a long period, the arteries and heart may not function properly.

Q-Can I discontinue using this tablet if I find that my blood pressure is in the normal range?

Continue taking this medicine as recommended by the medical expert even if you think you are keeping well. You may need blood pressure medicines for a lifetime. Do not discontinue this tablet abruptly and if you do so, it can lead to fatal heart problems.

Q-Can I take Hydrochlorothiazide 25 mg for the long term?

Take this tablet as told by the healthcare expert. This tablet is prescribed for long-term treatment. It accompanies serious risks if not taken as per the prescriptions. If you discontinue taking it suddenly or do not take it or do not take it as per the prescription, your high bp problem and swelling may get severe.

 Q-Will my blood pressure levels elevate if I stop taking Hydrochlorothiazide 25 mg suddenly?

Most patients having high blood pressure will not face any health issues, but if they discontinue this medicine, the condition can get worst. It can elevate blood pressure levels and increase the risk of heart stroke or heart disease. You should check your blood pressure frequently.

Q-What other changes can I incorporate into my lifestyle while Hydrochlorothiazide 25 mg tablet?

This tablet is just a part of the treatment regime which also includes regular exercise, a balanced diet, quitting smoking habits, limiting the consumption of alcohol, and managing weight. You can have normal food while taking this tablet, but reduce the amount of salt in your meals.

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